Maternal circulating exosomal miR-185-5p levels as a predictive biomarker in patients with recurrent pregnancy loss.

Yujing XiongZheng FangJie DongShuqiang ChenJiaqin MaoWanlin ZhangLi HaiJing ZhouXiaohong Wang

Published in: Journal of assisted reproduction and genetics (2023)

The current study, for the first time, successfully constructed the correlation between maternal circulating exosomal miR-185-5p expression pattern and RPL, which may be involved in the pathogenesis of RPL by downregulating the VEGFA of dNK cells and perturbing angiogenesis at the maternal-fetal interface.

Keyphrases

pregnancy outcomes
birth weight
induced apoptosis
poor prognosis
endothelial cells
preterm birth
vascular endothelial growth factor
oxidative stress
signaling pathway
body mass index
endoplasmic reticulum stress
long non coding rna
binding protein
weight loss