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Aggressive Variant of Hepatic Epstein-Barr Virus-Associated Inflammatory Pseudotumor-like Follicular Dendritic Cell Sarcoma with PD-L1 and SSTR2a Expression.

Madhur PardasaniMuthukumarassamy RajakannuMukul VijRajesh RajalingamMohamed Rela
Published in: Diagnostics (Basel, Switzerland) (2023)
An aggressive Epstein-Barr virus (EBV)-associated inflammatory pseudotumor-like follicular dendritic cell (IPT-like FDC) sarcoma is reported in an adult female. The patient developed multifocal recurrence and passed away 13 months after the initial surgical resection. A bright field microscopic examination of the tumor demonstrated a classical growth pattern and the diffuse expression of Programmed death ligand 1 (PD-L1) and somatostatin receptor 2a (SSTR2a).
Keyphrases
  • epstein barr virus
  • dendritic cells
  • diffuse large b cell lymphoma
  • poor prognosis
  • regulatory t cells
  • oxidative stress
  • binding protein
  • immune response
  • long non coding rna
  • low grade
  • high grade