Coronary lesion complexity in patients with heterozygous familial hypercholesterolemia hospitalized for acute myocardial infarction: data from the RICO survey.
Hermann YaoMichel FarnierLaura TribouillardFrédéric ChaguePhilippe BrunelMaud MazaDamien BrunetLuc RochetteFlorence BichatYves CottinMarianne ZellerPublished in: Lipids in health and disease (2021)
FH patients with acute MI had more severe CAD, characterized by complex anatomical features that are mainly dependent on the LDL-cholesterol burden. Our findings reinforce the need for more aggressive preventive strategies in these high-risk patients, and for intensive lipid-lowering therapy as secondary prevention.
Keyphrases
- acute myocardial infarction
- end stage renal disease
- coronary artery disease
- early onset
- ejection fraction
- newly diagnosed
- chronic kidney disease
- coronary artery
- prognostic factors
- peritoneal dialysis
- heart failure
- big data
- aortic stenosis
- stem cells
- patient reported outcomes
- risk factors
- fatty acid
- bone marrow
- patient reported
- smoking cessation