Macrophage and CD8 T cell discordance are associated with acute lung allograft dysfunction progression.

Daniel R CalabreseChristina A EkstrandShivaram YellamilliJonathan P SingerSteven R HaysLorriana E LeardRupal J ShahAida VenadoNicholas A KolaitisAlyssa PerezAlexis CombesJohn R Greenland

Published in: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation (2024)

BAL anti-inflammatory macrophages may protect against CLAD by suppressing CD8 T cells. These populations merit functional and longitudinal assessment in additional cohorts.

Keyphrases

anti inflammatory
liver failure
respiratory failure
adipose tissue
oxidative stress
drug induced
aortic dissection
cross sectional
kidney transplantation
genetic diversity
hepatitis b virus
intensive care unit
mechanical ventilation