Incidence of catheter-associated urinary tract infections by Gram-negative bacilli and their ESBL and carbapenemase production in specialized hospitals of Bahir Dar, northwest Ethiopia.
Zelalem AsmareTewachew AwokeChalachew GenetAlemale AdmasAddisu MeleseWondemagegn MuluPublished in: Antimicrobial resistance and infection control (2024)
Incidence of CAUTI with Gram-negative bacilli is high. As most of the GNB isolates are MDR and showed a super high rate of resistance to amoxicillin-clavulanic and third-generation cephalosporins, empirical treatment with these substances is virtually ineffective in patients with suspected GNB infection in Ethiopia. The expression of ESBL and carbapenemase among GNB isolates is also a concern. Therefore, improved infection prevention and control measures, careful use of catheters and third generation of cephalosporins are needed to improve patient outcomes and reduce the burden of CAUTIs and the spreading of antimicrobial resistance.
Keyphrases
- gram negative
- multidrug resistant
- klebsiella pneumoniae
- antimicrobial resistance
- urinary tract infection
- drug resistant
- acinetobacter baumannii
- risk factors
- escherichia coli
- poor prognosis
- healthcare
- genetic diversity
- palliative care
- drinking water
- long non coding rna
- binding protein
- combination therapy
- ultrasound guided
- cystic fibrosis