Prevention of chemotherapy-induced premature ovarian insufficiency in mice by scaffold-based local delivery of human embryonic stem cell-derived mesenchymal progenitor cells.

Eun-Young ShinDa-Seul KimMin Ji LeeAh Reum LeeSung Han ShimSeung Woon BaekDong Keun HanDong Ryul Lee

Published in: Stem cell research & therapy (2021)

HA GEL scaffolds can be used as new delivery platforms for ESC-MPC therapy, and this method may provide a novel option for the clinical treatment of chemotherapy-induced POI.

Keyphrases

chemotherapy induced
stem cells
endothelial cells
tissue engineering
induced pluripotent stem cells
type diabetes
high fat diet induced
cell therapy
pluripotent stem cells
mesenchymal stem cells
replacement therapy
hyaluronic acid
skeletal muscle
wound healing