CLIC4 Function in the Epithelial-Mesenchymal Transition of Epithelial Odontogenic Lesions.

Mariana Carvalho Xerez Caio César da Silva Barros Maurília Raquel de Souto Medeiros Rodrigo Porpino MafraHévio Freitas de LucenaÉricka Janine Dantas da Silveira Antônio de Lisboa Lopes Costa

Published in: Head and neck pathology (2024)

CLIC4 seems to regulate the epithelial-mesenchymal transition, modifying E-cadherin and Vimentin expression. In mesenchymal cells, CLIC4 may play a role in fibroblast-myofibroblast transdifferentiation. CLIC4 may be associated with epithelial odontogenic lesions with aggressive biological behavior.

Keyphrases

epithelial mesenchymal transition
transforming growth factor
induced apoptosis
signaling pathway
poor prognosis
cell cycle arrest
bone marrow
stem cells
endoplasmic reticulum stress
cell death
long non coding rna
binding protein
cell proliferation