Treatment of primary biliary cholangitis ursodeoxycholic acid non-responders: A systematic review.
Duminda SuraweeraHarman RahalMelissa JimenezMatthew ViramontesGina ChoiSammy SaabPublished in: Liver international : official journal of the International Association for the Study of the Liver (2017)
In patients with PBC refractory to UDCA, obeticholic acid or a fibrate is a reasonable choice as an adjunctive treatment to UDCA. Further investigation with randomized controlled trials is needed to provide high quality evidence to formulate standardized therapies in this difficult to treat population.