Old but Fancy: Curcumin in Ulcerative Colitis-Current Overview.
Aleksandra Pituch-ZdanowskaŁukasz DembińskiAleksandra BanaszkiewiczPublished in: Nutrients (2022)
Ulcerative colitis (UC) is one of the inflammatory bowel diseases (IBD). It is a chronic autoimmune inflammation of unclear etiology affecting the colon and rectum, characterized by unpredictable exacerbation and remission phases. Conventional treatment options for UC include mesalamine, glucocorticoids, immunosuppressants, and biologics. The management of UC is challenging, and other therapeutic options are constantly being sought. In recent years more attention is being paid to curcumin, a main active polyphenol found in the turmeric root, which has numerous beneficial effects in the human body, including anti-inflammatory, anticarcinogenic, and antioxidative properties targeting several cellular pathways and making an impact on intestinal microbiota. This review will summarize the current knowledge on the role of curcumin in the UC therapy.
Keyphrases
- ulcerative colitis
- anti inflammatory
- endothelial cells
- oxidative stress
- chronic obstructive pulmonary disease
- healthcare
- working memory
- multiple sclerosis
- stem cells
- stress induced
- drug induced
- pluripotent stem cells
- mesenchymal stem cells
- rheumatoid arthritis
- intensive care unit
- drug delivery
- cell therapy
- extracorporeal membrane oxygenation
- smoking cessation
- respiratory failure