Antimicrobial peptides in human corneal tissue of patients with fungal keratitis.

Imran MohammedDebasmita MohantyDalia G SaidManas Ranjan BarikMamatha M ReddyAhmed AlsaadiSujata Das Harminder Singh Singh DuaRuchi Mittal

Published in: The British journal of ophthalmology (2020)

AMP expression is a consistent feature of FK, but not all AMPs are equally expressed. HBD-1 and -2 are most consistently expressed and LL-37 the least, suggesting some specificity of AMP expression related to FK. These results will help to identify HBD sequence templates for designing FK-specific peptides to test for therapeutic potential.

Keyphrases

poor prognosis
protein kinase
endothelial cells
machine learning
binding protein
long non coding rna
optical coherence tomography
induced pluripotent stem cells
drug induced
cataract surgery