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Clinico-pathological phenotypes of Systemic Sclerosis associated myopathy: analysis of a multicenter large cohort.

Ana Matas-GarcíaAlfredo Guillén-Del-CastilloBoris KislukAlbert Selva-O'CallaghanGerard EspinosaSergio Prieto-GonzálezPedro Moreno LozanoGlòria GarrabouJosep María Grau-JunyentCarmen Pilar Simeon-AznarJose Cesar Milisenda
Published in: Rheumatology (Oxford, England) (2022)
Patients with SSc-associated myopathy require a comprehensive approach that encompasses clinical, serological, and histopathological aspects given their outcome predictive capacity. At least two different phenotypes can be drawn considering clinic-pathological features. Significant differences are delineated between both a fibrotic and an inflammatory phenotype.
Keyphrases
  • systemic sclerosis
  • interstitial lung disease
  • late onset
  • muscular dystrophy
  • primary care
  • oxidative stress
  • cross sectional
  • early onset
  • clinical trial
  • double blind
  • rheumatoid arthritis
  • duchenne muscular dystrophy