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Real-world outcomes of nivolumab plus ipilimumab combination therapy for advanced renal cell carcinoma in Japanese patients: data with a minimum of 3 years of follow-up.

Hiroki IshiharaNemoto YukiRyo IshiyamaTakashi IkedaYuki KobariHironori FukudaKazuhiko YoshidaHiroaki ShimmuraYasunobu HashimotoJunpei IizukaTsunenori KondoToshio Takagi
Published in: Japanese journal of clinical oncology (2024)
The 3-year follow-up data showed that nivolumab plus ipilimumab combination therapy exhibited a feasible effectiveness in real-world Japanese patients with advanced renal cell carcinoma. Accordingly, the high risk of adverse event development, which often requires treatment withdrawal and corticosteroid administration, should be considered.
Keyphrases
  • combination therapy
  • renal cell carcinoma
  • electronic health record
  • big data
  • randomized controlled trial
  • systematic review
  • metabolic syndrome
  • adipose tissue
  • artificial intelligence
  • adverse drug
  • drug induced