Increased Maternal Care Rescues Altered Reinstatement Responding Following Moderate Prenatal Alcohol Exposure.
Sarah L OlguinAmber ZimmermanHaikun ZhangAndrea AllanKevin C CaldwellJonathan L BrigmanPublished in: Alcoholism, clinical and experimental research (2019)
Together these results demonstrate that even moderate PAE is sufficient to alter control over reward seeking as measured by reinstatement. Importantly, an early-life intervention previously shown to improve cognitive outcomes in PAE mice was sufficient to ameliorate this effect.
Keyphrases
- early life
- high intensity
- randomized controlled trial
- healthcare
- pregnant women
- palliative care
- mental health
- high fat diet induced
- mouse model
- birth weight
- quality improvement
- pregnancy outcomes
- adipose tissue
- alcohol consumption
- metabolic syndrome
- chronic pain
- insulin resistance
- affordable care act
- weight loss
- body mass index
- weight gain