miR-23b Negatively Regulates Sepsis-Induced Inflammatory Responses by Targeting ADAM10 in Human THP-1 Monocytes.
Wenying ZhangFurong LuYuliu XieYao LinTian ZhaoShoubao TaoZhipeng LaiNing WeiRuoxuan YangYiming ShaoJunbing HePublished in: Mediators of inflammation (2019)
The present study demonstrated that miR-23b negatively regulated LPS-induced inflammatory responses by targeting ADAM10. The molecular regulatory mechanism of miR-23b in ADAM10 expression and sepsis-induced inflammatory consequences may provide potential therapeutic targets for sepsis.