Characterization of two novel phosphodiesterase 2 inhibitors Hcyb1 and PF-05180999 on depression- and anxiety-like behavior.
Yuqing YanYuhan ZhaoYue LuAbhinav P AcharyaWei WangChang-Guo ZhanJianghong YeFu DuXiongwei ZhuYing XuPublished in: The international journal of neuropsychopharmacology (2023)
The results extend the previous studies and validate that PDE2A is a tractable target for drug development in the treatment of emotional disorders such as depression and anxiety.
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