Chang-Guo Zhan

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 27

Top Topics

Induced Pluripotent Stem Cells

Molecular Dynamics Simulations

Machine Learning

Respiratory Syndrome Coronavirus

Top Venues

ACS chemical neuroscience

The journal of physical chemistry. B

Proceedings of the National Academy of Sciences of the United States of America

Addiction biology

This page only lists publications with an associated author ORCID identifier.

Publications

Hongsong Feng, Rui Wang, Chang-Guo Zhan, Guo-Wei Wei
Multiobjective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex. Journal of medicinal chemistry (2023)
Fang Zheng, Shurong Hou, Liu Xue, Wenchao Yang, Chang-Guo Zhan
Human Butyrylcholinesterase Mutants for (-)-Cocaine Hydrolysis: A Correlation Relationship between Catalytic Efficiency and Total Hydrogen Bonding Energy with an Oxyanion Hole. The journal of physical chemistry. B (2023)
Max Zhan, Shurong Hou, Linyue Shang, Xiabin Chen, Chang-Guo Zhan, Fang Zheng
Kinetic characterization of an efficient cocaine hydrolase against toxic metabolites of cocaine. Organic & biomolecular chemistry (2023)
Yuqing Yan, Yuhan Zhao, Yue Lu, Abhinav P Acharya, Wei Wang, Chang-Guo Zhan, Jianghong Ye, Fu Du, Xiongwei Zhu, Ying Xu
Characterization of two novel phosphodiesterase 2 inhibitors Hcyb1 and PF-05180999 on depression- and anxiety-like behavior. The international journal of neuropsychopharmacology (2023)
Alexander H Williams, Chang-Guo Zhan
Staying Ahead of the Game: How SARS-CoV-2 has Accelerated the Application of Machine Learning in Pandemic Management. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy (2023)
Alexander H Williams, Chang-Guo Zhan
Fast Prediction of Binding Affinities of SARS-CoV-2 Spike Protein and Its Mutants with Antibodies through Intermolecular Interaction Modeling-Based Machine Learning. The journal of physical chemistry. B 126 (28) (2022)
Alexander H Williams, Chang-Guo Zhan
Generalized Methodology for the Quick Prediction of Variant SARS-CoV-2 Spike Protein Binding Affinities with Human Angiotensin-Converting Enzyme II. The journal of physical chemistry. B 126 (12) (2022)
Jing Deng, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zheng
Gender differences in cocaine-induced hyperactivity and dopamine transporter trafficking to the plasma membrane. Addiction biology 27 (6) (2022)
Ling Guo, Emily E Morin, Minzhi Yu, Ling Mei, Maria V Fawaz, Qian Wang, Yaxia Yuan, Chang-Guo Zhan, Theodore J Standiford, Anna A Schwendeman, Xiang-An Li
Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice. Science signaling 15 (725) (2022)
Fang Zheng, Zhenyu Jin, Jing Deng, Xiabin Chen, Xirong Zheng, Guojun Wang, Kyungbo Kim, Linyue Shang, Ziyuan Zhou, Chang-Guo Zhan
Development of a Highly Efficient Long-Acting Cocaine Hydrolase Entity to Accelerate Cocaine Metabolism. Bioconjugate chemistry 33 (7) (2022)
Bahadır Bülbül, Kai Ding, Chang-Guo Zhan, Gamze Çiftçi, Kemal Yelekçi, Merve Gürboğa, Özlem Bingöl Özakpınar, Esra Aydemir, Deniz Baybağ, Fikrettin Şahin, Necla Kulabaş, Sinem Helvacıoğlu, Mohammad Charehsaz, Esra Tatar, Süheyla Özbey, İlkay Küçükgüzel
Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity. Molecular diversity (2022)
Jing Deng, Ting Zhang, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zheng
Recovery of dopaminergic system after cocaine exposure and impact of a long-acting cocaine hydrolase. Addiction biology 27 (4) (2022)
Zhe Li, Yuxi Lin, Yi-You Huang, Runduo Liu, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo
Reply to Ma and Wang: Reliability of various in vitro activity assays on SARS-CoV-2 main protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America 118 (8) (2021)
Jing Deng, Kyungbo Kim, Xirong Zheng, Linyue Shang, Chang-Guo Zhan, Fang Zheng
Cocaine hydrolase blocks cocaine-induced dopamine transporter trafficking to the plasma membrane. Addiction biology (2021)
Zhe Li, Runduo Liu, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo
Reply to Behnam and Klein: Potential role of the His-tag in C-terminal His-tagged SARS-CoV-2 main protease. Proceedings of the National Academy of Sciences of the United States of America 118 (36) (2021)
Alexander H Williams, Chang-Guo Zhan
Fast Prediction of Binding Affinities of the SARS-CoV-2 Spike Protein Mutant N501Y (UK Variant) with ACE2 and Miniprotein Drug Candidates. The journal of physical chemistry. B 125 (17) (2021)
Charles Adeniran, Yaxia Yuan, Sarah E Davis, Ciai Lin, Jiahui Xu, Jun Zhu, Chang-Guo Zhan
Binding Mode of Human Norepinephrine Transporter Interacting with HIV-1 Tat. ACS chemical neuroscience 12 (9) (2021)
Zhe Li, Xin Li, Yi-You Huang, Yaoxing Wu, Runduo Liu, Lingli Zhou, Yuxi Lin, Deyan Wu, Lei Zhang, Hao Liu, Ximing Xu, Kunqian Yu, Yuxia Zhang, Jun Cui, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo
Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs. Proceedings of the National Academy of Sciences of the United States of America 117 (44) (2020)
Chun-Hui Zhang, Kyungbo Kim, Zhenyu Jin, Fang Zheng, Chang-Guo Zhan
Systematic Structure-Based Virtual Screening Approach to Antibody Selection and Design of a Humanized Antibody against Multiple Addictive Opioids without Affecting Treatment Agents Naloxone and Naltrexone. ACS chemical neuroscience 12 (1) (2020)
Zhe Li, Yunsong Zhao, Huifang Zhou, Hai-Bin Luo, Chang-Guo Zhan
Catalytic Roles of Coenzyme Pyridoxal-5'-phosphate (PLP) in PLP-dependent Enzymes: Reaction Pathway for Methionine-γ-lyase-catalyzed L-methionine Depletion. ACS catalysis 10 (3) (2020)
Jing-Fang Yang, Alexander H Williams, Narsimha R Penthala, Paul L Prather, Peter A Crooks, Chang-Guo Zhan
Binding Modes and Selectivity of Cannabinoid 1 (CB1) and Cannabinoid 2 (CB2) Receptor Ligands. ACS chemical neuroscience 11 (20) (2020)
Zhe Li, Yiyou Huang, Yinuo Wu, Jingyi Chen, Deyan Wu, Chang-Guo Zhan, Hai-Bin Luo
Absolute Binding Free Energy Calculation and Design of a Subnanomolar Inhibitor of Phosphodiesterase-10. Journal of medicinal chemistry 62 (4) (2019)
Wen Zhang, Vitaliy M Sviripa, Liliia M Kril, Tianxin Yu, Yanqi Xie, William Brad Hubbard, Patrick G Sullivan, Xi Chen, Chang-Guo Zhan, Yang Yang-Hartwich, B Mark Evers, Brett T Spear, Roberto Gedaly, David S Watt, Chunming Liu
An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors. Journal of medicinal chemistry 62 (24) (2019)
Shuo Zhou, Ziyuan Zhou, Kai Ding, Yaxia Yuan, Fang Zheng, Chang-Guo Zhan
In Silico Observation of the Conformational Opening of the Glutathione-Binding Site of Microsomal Prostaglandin E2 Synthase-1. Journal of chemical information and modeling 59 (9) (2019)
Haifeng Huang, Lei Fang, Liu Xue, Ting Zhang, Kyungbo Kim, Shurong Hou, Fang Zheng, Chang-Guo Zhan
PEGylation but Not Fc-Fusion Improves in Vivo Residence Time of a Thermostable Mutant of Bacterial Cocaine Esterase. Bioconjugate chemistry 30 (12) (2019)
Yaxia Yuan, Jun Zhu, Chang-Guo Zhan
Flipped Phenyl Ring Orientations of Dopamine Binding with Human and Drosophila Dopamine Transporters: Remarkable Role of Three Nonconserved Residues. ACS chemical neuroscience 9 (6) (2018)
Jianzhuang Yao, Xiabin Chen, Fang Zheng, Chang-Guo Zhan
Catalytic Reaction Mechanism for Drug Metabolism in Human Carboxylesterase-1: Cocaine Hydrolysis Pathway. Molecular pharmaceutics 15 (9) (2018)