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Evaluation of the stability of ceftazidime/avibactam in elastomeric infusion devices used for outpatient parenteral antimicrobial therapy utilizing a national stability protocol framework.

Saiyuri NaickerJason Alexander RobertsHayoung WonSteven C WallisSean UnwinConor JamiesonTim HillsMark GilchristMark SantilloR Andrew SeatonFelicity DrummondFekade Bruck Sime
Published in: JAC-antimicrobial resistance (2024)
Whilst not meeting the strict UK YCD criteria for ≤5% degradation, ceftazidime/avibactam may be acceptable to administer as a continuous 12 hourly infusion in those territories where degradation of ≤10% is deemed acceptable.
Keyphrases
  • gram negative
  • multidrug resistant
  • low dose
  • klebsiella pneumoniae
  • staphylococcus aureus
  • randomized controlled trial
  • escherichia coli
  • stem cells
  • mesenchymal stem cells