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Influence of the new standardized clinical cryopreservation/slow thawing protocol on immunogenicity of arterial allografts in rats.

Jan HrubyRudolf SpundaPavel MerickaMikulas MlcekOndrej PechaKatrin SplithMoritz SchmelzleFelix KrenzienJaroslav LindnerMiroslav SpacekIvan Matia
Published in: PloS one (2020)
Aortal wall histology of rat allografts treated by our new standardized clinical cryopreservation/slow thawing protocol was comparable to that of the cryopreserved isografts on day 30 posttranspant. The immunogenicity of cryopreserved aortal allografts was significantly lower compared to that of cold-stored aortal allografts.
Keyphrases
  • randomized controlled trial
  • umbilical cord
  • oxidative stress
  • cord blood
  • mesenchymal stem cells