Reactive oxygen species-dependent apoptosis induction by water extract of Citrus unshiu peel in MDA-MB-231 human breast carcinoma cells.

Min Yeong Kim Eun Ok Choi Hyun HwangBo Da Hye Kwon Kyu Im Ahn Hong Jae Kim Seon Yeong Ji Su Hyun Hong Jin-Woo Jeong Gi Young Kim Cheol Park Young Hyun Choi

Published in: Nutrition research and practice (2018)

These results suggest that WECU suppressed proliferation of MDA-MB-231 cells by activating extrinsic and intrinsic apoptosis pathways in a ROS-dependent manner.

Keyphrases

cell cycle arrest
cell death
reactive oxygen species
pi k akt
signaling pathway
endothelial cells
oxidative stress
induced apoptosis
induced pluripotent stem cells
dna damage
cell proliferation
pluripotent stem cells