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Impact of Preeclampsia on the Relationship between Maternal Asthma and Offspring Asthma. An Observation from the VDAART Clinical Trial.

Hooman MirzakhaniVincent J CareyThomas F McElrathWeiliang QiuBruce W HollisGeorge T O'ConnorRobert S ZeigerLeonard BacharierAugusto A LitonjuaScott T Weiss
Published in: American journal of respiratory and critical care medicine (2019)
Preeclampsia is associated with increased risk of early life childhood asthma in children less than 3 years old over and above that associated with maternal asthma alone. The results implicate the interplay between maternal factors as strong predictors of offspring asthma and in utero maternal-fetal immune perturbations and developmental dysregulations associated with preeclampsia.
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