Epigenetic regulation of nuclear processes in fungal plant pathogens.
H Martin KramerDavid E CookMichael F SeidlBart P H J ThommaPublished in: PLoS pathogens (2023)
Through the association of protein complexes to DNA, the eukaryotic nuclear genome is broadly organized into open euchromatin that is accessible for enzymes acting on DNA and condensed heterochromatin that is inaccessible. Chemical and physical alterations to chromatin may impact its organization and functionality and are therefore important regulators of nuclear processes. Studies in various fungal plant pathogens have uncovered an association between chromatin organization and expression of in planta-induced genes that are important for pathogenicity. This review discusses chromatin-based regulation mechanisms as determined in the fungal plant pathogen Verticillium dahliae and relates the importance of epigenetic transcriptional regulation and other nuclear processes more broadly in fungal plant pathogens.
Keyphrases
- cell wall
- genome wide
- gene expression
- transcription factor
- dna damage
- gram negative
- dna methylation
- circulating tumor
- antimicrobial resistance
- cell free
- single molecule
- poor prognosis
- physical activity
- mental health
- high glucose
- multidrug resistant
- diabetic rats
- endothelial cells
- cystic fibrosis
- nucleic acid
- oxidative stress
- long non coding rna
- candida albicans
- amino acid
- genome wide identification
- plant growth