Cytotoxic Potential, Metabolic Profiling, and Liposomes of Coscinoderma sp. Crude Extract Supported by in silico Analysis.
Arafa MusaAbeer H ElmaidomyAhmed M SayedSami I AlzareaMohammad M Al-SaneaEhab M MostafaOmina Magdy HendawyMohamed Abdelwahab AbdelgawadKhayrya A YoussifHesham RefaatEman AlaaeldinUsama Ramadan AbdelmohsenPublished in: International journal of nanomedicine (2021)
Encapsulation of both the hydrophilic and the lipophilic components of the extract within the lipid-based nanovesicles enhanced the cellular uptake and accessibility of the entrapped cargo. This study introduces liposomal nano-vesicles as a promising approach to improve the therapeutic potential of sponge-derived extracts.