Porcupine Quills Keratin Peptides Induces G0/G1 Cell Cycle Arrest and Apoptosis Via p53/p21 Pathway and Caspase Cascade Reaction in MCF-7 Breast Cancer Cells.

Kun WangYanan XuHaozhang HuangDong PengJianping ChenPan LiBing Du

Published in: Journal of the science of food and agriculture (2023)

These findings indicated that PQKPs suppressed the proliferation of MCF-7 breast cancer cells by triggering apoptosis and G0/G1 cell cycle arrest. Moreover, the outcome of this study will bring fresh insights into the production and application of animal byproducts. This article is protected by copyright. All rights reserved.

Keyphrases

cell cycle arrest
breast cancer cells
cell death
pi k akt
signaling pathway
drinking water
cell proliferation
oxidative stress
amino acid
endoplasmic reticulum stress