Epigenetic Regulation of the Expression of T Cell Stimulatory and Inhibitory Factors by Histone H3 Lysine Modification Enzymes and Its Prognostic Roles in Glioblastoma.
Sang Hyuk LeeSeung Hwan KimTaek Min NamJi Hwan JangKyu Hong KimYoung-Sam LeeMinseok S KimMee-Seon KimSung Yup JinMoon Ok LeeSung-Hun LeeYoung Zoon KimPublished in: Journal of Korean medical science (2023)
These findings suggest that the expression of certain T cell co-stimulatory factors, such as CD28 and CD 137, and co-inhibitory factors, such as CTLA4 and PD-L1 are associated with prognosis of glioblastoma patients.