Comparative Effectiveness of Device-Aided Therapies on Quality of Life and Off-Time in Advanced Parkinson's Disease: A Systematic Review and Bayesian Network Meta-analysis.

Angelo Antonini Rajesh Pahwa Per Odin Stuart H Isaacson Aristide MerolaLin WangPrasanna L KandukuriAli Alobaidi Connie H YanYanjun BaoCindy ZadikoffJuan Carlos ParraLars BergmannKallol Ray Chaudhuri

Published in: CNS drugs (2022)

This NMA found that LCIG and DBS were associated with superior improvement in off-time and PD-related QoL compared with CSAI and BMT at 6 months after treatment initiation. This comparative effectiveness research may assist providers, patients, and caregivers in the selection of the optimal device-aided therapy.

Keyphrases

systematic review
end stage renal disease
newly diagnosed
ejection fraction
peritoneal dialysis
palliative care
randomized controlled trial
stem cells
patient reported outcomes
mesenchymal stem cells
bone marrow
drug induced