Lack of defined apheresis collection criteria in publicly available CAR-T cell clinical trial descriptions: Comprehensive review of over 600 studies.

Suzanne R ThibodeauxNicole A AquiYara A ParkJennifer SchneidermanLeon L SuJeffrey L WintersAbba C ZubairJoseph SchwartzHien D Liunull null

Published in: Journal of clinical apheresis (2022)

Apheresis collection of CAR-T cell products is not well-defined in clinical study descriptions and the context is inconsistent. Laboratory parameters useful for apheresis collection are variably present and do not consistently align with current practices. Further exploration, and clinical guideline development will encourage alignment of apheresis collections for CAR-T cell products.

Keyphrases

clinical trial
primary care
healthcare
randomized controlled trial
study protocol
open label
phase ii