Free fatty acid receptors, G protein-coupled receptor 120 and G protein-coupled receptor 40, are essential for oil-induced gastric inhibitory polypeptide secretion.
Akiko SankodaNorio HaradaTomoko KatoEri IkeguchiKanako IwasakiShunsuke YamaneYuki MurataAkira HirasawaNobuya InagakiPublished in: Journal of diabetes investigation (2019)
Oil-induced GIP secretion is triggered by the two major fatty acid receptors, GPR120 and GPR40, without changing K-cell number or K-cell characteristics.