Optimizing the Design of Clinical Trials to Evaluate the Efficacy of Function-Promoting Therapies.

Shalender BhasinPeggy M CawthonRosaly Correa-de-AraujoThomas W StorerElena Volpi Anne B NewmanWaly DiohCendrine TouretteWilliam J EvansRoger A Fielding

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2023)

Collaborations among academic investigators, NIH, FDA, pharmaceutical industry, patients, and professional societies are needed to conduct well-designed trials of function-promoting pharmacological agents with and without multicomponent functional training.

Keyphrases

clinical trial
end stage renal disease
newly diagnosed
chronic kidney disease
ejection fraction
peritoneal dialysis
randomized controlled trial
prognostic factors
patient reported outcomes
phase ii
virtual reality
phase iii