Targeting STAT3 signaling pathway by curcumin and its analogues for breast cancer: A narrative review.

Maryam GolmohammadiMohammad Yassin ZamanianAhmed Muzahem Al-AniThaer L JabbarAli Kamil KareemZeinab Hashem AghaeiHossein TaherniaAhmed HjaziSaad Abdul-Ridh JissirElham Hakimizadeh

Published in: Animal models and experimental medicine (2024)

CUR and its analogues hold promise as effective adjuvant treatments for BC by targeting the STAT3 signaling pathway. These compounds provide new insights into the mechanisms of action of CUR and its potential to enhance the effectiveness of BC therapies.

Keyphrases

signaling pathway
pi k akt
cell proliferation
molecular docking
epithelial mesenchymal transition
induced apoptosis
randomized controlled trial
early stage
systematic review
structure activity relationship
cancer therapy
machine learning
young adults
artificial intelligence
childhood cancer