Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis: Observational and Mendelian Randomization Analyses.
Michael Robert ChongSukrit NarulaRobert W MortonConor JudgeLoubna AkhabirNathan CawteNazia PathanRicky LaliPedrum Mohammadi-ShemiraniAshkan ShoamaneshMartin O'DonnellSalim YusufPeter LanghorneGuillaume ParéPublished in: Neurology (2021)
This study provides class II evidence that low buffy coat mtDNA-CN (>1-standard deviation) was associated with worse baseline severity and 1-month outcomes in patients with ischemic or hemorrhagic stroke.