Decreased expression of annexin A2 and loss of its association with vascular endothelial growth factor leads to the deficient trophoblastic invasion in preeclampsia.
Komal RuikarManjunatha AithalaPraveenkumar ShettyUdupi Shastry DineshAnil BargaleRoshni SadashivSarathkumar Edachery VeeduVitthal KhodeAsha NeraviPrakash PatilPublished in: Journal of basic and clinical physiology and pharmacology (2021)
The diminished expression of VEGF and ANXA2 in placenta may be associated with the defective angiogenesis and which may possibly play a vital role in PE pathogenesis.