Family history and the natural history of colorectal cancer: systematic review.
Nora B HenriksonElizabeth M WebberKatrina A GoddardAaron ScrolMargaret A PiperMarc S WilliamsDoris T ZallenNed CalongeTheodore G GaniatsA Cecile J W JanssensAnn ZauberIris Lansdorp-VogelaarMarjolein van BallegooijenEvelyn P WhitlockPublished in: Genetics in medicine : official journal of the American College of Medical Genetics (2015)
Stratification based on polygenic and/or multifactorial risk assessment may mature to the point of displacing family history-based approaches, but for the foreseeable future, family history may remain a valuable clinical tool for identifying individuals at increased risk for CRC.