Immune profiling of mouse lung adenocarcinoma paraffin tissues using multiplex immunofluorescence panel: a pilot study.

Jie ZhaiAuriole TamegnonMei JiangRenganayaki Krishna PandurenganEdwin Roger Parra Cuentes

Published in: Laboratory animal research (2024)

Comprehensive immune profiling using mIF in translational studies improves our ability to correlate the PD-1/PD-L1 axis and spatial distribution of lymphocytes and macrophages in mouse lung cancer cells to provide new cues for immunotherapy, that can be translated to human tumors for cancer intervention.

Keyphrases

endothelial cells
single cell
papillary thyroid
randomized controlled trial
gene expression
squamous cell
high throughput
peripheral blood
induced pluripotent stem cells
squamous cell carcinoma
case control
lymph node metastasis