External validity of type 2 diabetes clinical trials on cardiovascular outcomes for a multimorbid population.

Felippe Lazar Neto Thiago Bosco MendesPaulo Marcelo Pontes Gomes MatosJulio César de OliveiraMaria Helena Sampaio FavaratoChin An LinMilton Arruda Martins

Published in: Diabetes, obesity & metabolism (2021)

A considerable proportion of multimorbid patients would be eligible for recent antihyperglycaemic trials. This positive finding can be attributed to development guidance in diabetes trials and the different approach we took, in which we evaluated inclusion by trials as an aggregate.

Keyphrases

type diabetes
clinical trial
end stage renal disease
cardiovascular disease
glycemic control
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
randomized controlled trial
patient reported outcomes
insulin resistance
open label
patient reported