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Cerebrolysin after moderate to severe traumatic brain injury: prospective meta-analysis of the CAPTAIN trial series.

Johannes C VesterAnca D BuzoianuStefan I FlorianVolker HömbergSe-Hyuk KimTatia M C LeeChristian MatulaWai Sang PoonDorel SandescNicole von SteinbüchelStefan StrilciucPieter E VosKlaus von WildDafin F Muresanu
Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2021)
The meta-analysis of the CAPTAIN trials confirms the safety and efficacy of Cerebrolysin after moderate-severe TBI, opening a new horizon for neurorecovery in this field. Integration of Cerebrolysin into existing guidelines should be considered after careful review of internationally applicable criteria.
Keyphrases
  • severe traumatic brain injury
  • traumatic brain injury
  • high intensity
  • study protocol
  • phase iii
  • clinical trial
  • clinical practice
  • phase ii
  • randomized controlled trial