Empagliflozin and renal sodium-hydrogen exchange in healthy subjects.
Edoardo BiancalanaChiara RossiFrancesco RaggiMariarosaria DistasoDomenico TricòSimona BaldiEleuterio FerranniniAnna SoliniPublished in: The Journal of clinical endocrinology and metabolism (2023)
In healthy young volunteers, empagliflozin acutely increases urinary pH while inducing a substrate shift towards lipid utilization and ketogenesis, without significant changes in renal NHE3 protein expression.
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