Screening for obstructive sleep apnea (OSA) in children and adolescents with obesity: A scoping review of national and international pediatric obesity and pediatric OSA management guidelines.
Nicholas Beng Hui NgCarey Yun Shan LimSarah Caellainn Hui Lin TanYu Wah FooChanel Li Xuan TokYvonne Yijuan LimDaniel Yam Thiam GohKah Yin LokeYung Seng LeePublished in: Obesity reviews : an official journal of the International Association for the Study of Obesity (2024)
Obstructive sleep apnea (OSA) is a prevalent complication that affects up to 60% of children and adolescents with obesity. It is associated with poorer cardiometabolic outcomes and neurocognitive deficits. Appropriate screening and intervention for OSA are crucial in the management of children with obesity. We performed a scoping review of international and national pediatric obesity (n = 30) and pediatric OSA (n = 10) management guidelines to evaluate the recommendations on OSA screening in pediatric obesity. Sixteen (53%) of the pediatric obesity guidelines had incorporated OSA screening to varying extents, with no consistent recommendations on when and how to screen for OSA, and subsequent management of OSA in children with obesity. We provide our recommendations that are based on the strength and certainty of evidence presented. These include a clinical-based screening for OSA in all children with body mass index (BMI) ≥ 85th percentile or those with rapid BMI gain (upward crossing of 2 BMI percentiles) and the use of overnight polysomnography to confirm the diagnosis of OSA in those with high clinical suspicion. We discuss further management of OSA unique to children with obesity. An appropriate screening strategy for OSA would facilitate timely intervention that has been shown to improve cardiometabolic and neurocognitive outcomes.
Keyphrases
- obstructive sleep apnea
- positive airway pressure
- weight gain
- insulin resistance
- weight loss
- metabolic syndrome
- body mass index
- high fat diet induced
- type diabetes
- sleep apnea
- young adults
- clinical practice
- randomized controlled trial
- bipolar disorder
- traumatic brain injury
- adipose tissue
- physical activity
- high throughput
- glycemic control