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Impact of treatment with dimethyl fumarate on sleep quality in patients with relapsing-remitting multiple sclerosis: A multicentre Italian wearable tracker study.

Giancarlo ComiLetizia LeocaniLuigi Ferini-StrambiMarta RadaelliGloria D CostaRoberta LanzilloGiacomo LusValentina BianchiSebastiano TraccisFioravante CaponeLuigi Me GrimaldiGiuseppe SalemiAlessandra CardilloValentina Zipolinull null
Published in: Multiple sclerosis journal - experimental, translational and clinical (2023)
In patients with relapsing-remitting multiple sclerosis, the treatment with dimethyl fumarate was associated with improvements in patient-reported quality of sleep. Further randomised clinical trials are needed to confirm the benefits of long-term treatment with dimethyl fumarate.
Keyphrases
  • multiple sclerosis
  • clinical trial
  • sleep quality
  • white matter
  • patient reported
  • study protocol
  • randomized controlled trial
  • depressive symptoms
  • open label
  • double blind
  • combination therapy
  • replacement therapy