Impact of paternal education on epigenetic ageing in adolescence and mid-adulthood: a multi-cohort study in the USA and Mexico.

Brian Thomas JoyceTao GaoKalsea KossYinan ZhengAndres CardenasJonathan HeissAllan Carpenter JustKai ZhangLinda V Van HornNorrina Bai AllenPhilip GreenlandSheldon CohenPenny Gordon-LarsenColter MitchellSara McLanahanLisa SchneperDaniel NottermanSheryl L Rifas-ShimanEmily OkenMarie-France HivertRobert WrightAndrea BaccarelliDonald Lloyd-JonesLifang Hou

Published in: International journal of epidemiology (2021)

These findings suggest that EAA captures epigenetic impacts of paternal education independently of personal SES later in life. Longitudinal studies should explore these associations at different life stages and link them to health outcomes. EAA could be a useful biomarker of SES-associated health and provide important insight into the pathogenesis and prevention of chronic disease.

Keyphrases

healthcare
dna methylation
depressive symptoms
gene expression
quality improvement
public health
mental health
cross sectional
climate change
early life
human health