MERTK missense variants in three patients with retinitis pigmentosa.
Federica E PoliImran H YusufPenny CloustonMorag ShanksJennifer WhitfieldPeter Charbel IssaRobert E MacLarenPublished in: Ophthalmic genetics (2022)
is a promising candidate for viral-mediated gene replacement therapy. Moreover, one variant represents a single nucleotide transition, which is theoretically targetable with CRISPR-Cas9 base-editing.