Computable Phenotype of a Crohn's Disease Natural History Model.

Jacob A KurowskiJean-Paul AchkarDavid SuganoAlex MilinovichXinge JiJanine BaumanKeyonna R GriffinMichael W Kattan

Published in: Medical decision making : an international journal of the Society for Medical Decision Making (2022)

Using natural language processing, we defined the computable phenotype health state of Crohn's disease and developed patient-level longitudinal histories for health outcomes.Our methodology demonstrates the application of real-world data to define the progression of a chronic disease.The application of the model has the potential to provide better understanding of the true impact of a new therapy.

Keyphrases

public health
mental health
autism spectrum disorder
electronic health record
stem cells
human health
cross sectional
big data
climate change
artificial intelligence
smoking cessation