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Co-occurrence of apathy and impulse control disorders in Parkinson disease.

Bonnie M ScottRobert S EisingerMatthew R BurnsJanine LopesMichael S OkunAysegul GunduzDawn Bowers
Published in: Neurology (2020)
Motivational disturbances are common comorbid conditions in patients with PD. In addition, these complex behavioral syndromes interact with mood in clinically important ways that may influence the design of future clinical trials and the development of novel therapies. This study challenges the concept of apathy and ICD in PD as opposite ends of a spectrum.
Keyphrases
  • parkinson disease
  • clinical trial
  • deep brain stimulation
  • bipolar disorder
  • current status
  • randomized controlled trial
  • phase ii
  • physical activity
  • open label