Sirt1 expression is associated with CD31 expression in blood cells from patients with chronic obstructive pulmonary disease.
Ryo KatoShiro MizunoMaiko KadowakiKohei ShiozakiMasaya AkaiKen NakagawaTaku OikawaMasaharu IguchiKazuhiro OsanaiTakeshi IshizakiNorbert F VoelkelHirohisa TogaPublished in: Respiratory research (2016)
Sirt1 expression in blood cells from patients with COPD could be a biomarker for disease stability in patients with moderate COPD. MiR-34a may participate in apoptosis and/or senescence of EPCs in smokers. Decreased expression of CD31, CD34, and miR-126-3p potentially represents decreased numbers of EPCs in blood cell from patients with COPD.