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A structurally precise AgxAu25-x nanocluster based cancer theranostic platform with tri-targeting/in situ O2-generation/aggregation enhanced fluorescence imaging/photothermal-photodynamic therapies.

Ying YangYinlong ZhouShuxin WangXueyan WangXuan LiuAnjian XieYuhua ShenMan-Zhou Zhu
Published in: Chemical communications (Cambridge, England) (2021)
The photothermal and photodynamic performances of structurally precise oil-soluble AgxAu25-x (x ≤ 13) nanoclusters were first explored and they were solubilized into new assemblies to form a versatile cancer theranostic platform with tri-targeting/in situ O2-generation/aggregation enhanced fluorescence imaging/photothermal-photodynamic therapy effects, which will provide an important reference for precision theranostics at the atomic level in future.
Keyphrases
  • photodynamic therapy
  • fluorescence imaging
  • cancer therapy
  • papillary thyroid
  • squamous cell
  • drug delivery
  • high throughput
  • squamous cell carcinoma
  • lymph node metastasis
  • fatty acid
  • childhood cancer