Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue.

Benjamin JevansFay CooperYuliia FatieievaAntigoni GogolouYi-Ning KangRestuadi RestuadiDale MouldingPieter Vanden BergheIgor AdameykoNikhil ThaparPeter W AndrewsPaolo De CoppiAnestis Tsakiridis Conor J McCann

Published in: Gut (2024)

Our findings demonstrate, for the first time, the potential of hPSC-derived ENS progenitors to repopulate and increase functional responses in human HSCR patient colonic tissue.

Keyphrases

endothelial cells
induced pluripotent stem cells
pluripotent stem cells
case report
stem cells
bone marrow
risk assessment
climate change
mesenchymal stem cells
human health