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TB PCR in BAL and EBUS-TBNA samples for the diagnosis of pulmonary and mediastinal lymph node TB: retrospective TRiBE study.

Mirae ParkKartik KumarMeg ColemanLaura MartinGeorgina RussellPauline ScheelbeekAjit LalvaniGiovanni SattaOnn Min Kon
Published in: Thorax (2024)
Xpert Ultra had a significantly higher sensitivity compared with smear in both BAL and EBUS-TBNA samples. Xpert Ultra had a lower sensitivity compared with culture but comparable specificity with results being available within <24 hours. Trace readings in our low-incidence setting were associated with culture positivity in all BAL samples.
Keyphrases
  • lymph node
  • mycobacterium tuberculosis
  • high resolution
  • neoadjuvant chemotherapy
  • pulmonary tuberculosis
  • squamous cell carcinoma
  • cross sectional
  • heavy metals
  • risk assessment
  • radiation therapy
  • structural basis