Chronic kidney disease mortality trends in selected Central America countries, 1997-2013: clues to an epidemic of chronic interstitial nephritis of agricultural communities.
Pedro OrdunezF Javier NietoRamon MartinezPatricia SolizGloria P GiraldoSusan Anne MottWendy E HoyPublished in: Journal of epidemiology and community health (2018)
This study provides the most comprehensive mortality analysis of this epidemic published to date and confirms an excess of CKD-N18 mortality and its relation with the epidemic of CINAC. The overall trends and the mortality pattern among women, children and adolescents suggest that the heat stress-dehydration hypothesis cannot fully explain this epidemic and that other environmental factors, more likely agricultural practices and agrochemicals, may be causally involved.
Keyphrases
- chronic kidney disease
- cardiovascular events
- heat stress
- risk factors
- risk assessment
- end stage renal disease
- climate change
- heavy metals
- primary care
- randomized controlled trial
- cardiovascular disease
- type diabetes
- pregnant women
- coronary artery disease
- polycystic ovary syndrome
- metabolic syndrome
- adipose tissue
- human health
- insulin resistance