Dried blood spot cards: A reliable sampling method to detect human antibodies against rabies virus.
Laura DoornekampCarmen W E EmbregtsGeorgina I AronSimone GoeijenbierDavid A M C van de VijverEric C M van GorpCorine H GeurtsvanKesselPublished in: PLoS neglected tropical diseases (2020)
This is the first study that applies DBS for reliable detection of human antibodies against rabies virus. Both the FAVNt and Platelia-II ELISA demonstrate an acceptable performance on DBS, providing opportunities for rabies serology in remote areas. This technique could drastically ease studies evaluating (novel) rabies vaccination strategies and monitoring persisting immunity in humans at risk, living in rabies endemic regions.