Gonadal Function Recovery in Patients With Advanced Hodgkin Lymphoma Treated With a PET-Adapted Regimen: Prospective Analysis of a Randomized Phase III Trial (AHL2011).

Isabelle Demeestere Judith RacapeJulie DecheneJehan DupuisJudith TrotmanVirginie De WildeJulien LazaroviciHervé GhesquieresMohamed TouatiDavid SibonMagda AlexisAnne-Claire GacHannah MoattiEmmanuelle VirelizierHervé MaisonneuveDelphine PrangerRoch Houot Luc-Matthieu ForneckerAdrian TempesculMarc AndréRené-Olivier Casasnovas

Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2021)

Although both treatments affected ovarian reserve and spermatogenesis, the PET-driven strategy decreased the risk of gonadal dysfunction and infertility in advanced Hodgkin lymphoma.

Keyphrases

hodgkin lymphoma
phase iii
open label
clinical trial
pet ct
positron emission tomography
computed tomography
phase ii
double blind
pet imaging
placebo controlled
oxidative stress
polycystic ovary syndrome
randomized controlled trial
type diabetes
adipose tissue
insulin resistance
metabolic syndrome
newly diagnosed