CNTN5-/+or EHMT2-/+human iPSC-derived neurons from individuals with autism develop hyperactive neuronal networks.

Eric DeneaultMuhammad FaheemSean H WhiteDeivid C RodriguesSong SunWei WeiAlina PieknaTadeo ThompsonJennifer L HoweLeon ChalilVickie KwanSusan WalkerPeter PasceriFrederick P RothRyan Kc YuenKarun K Singh James Ellis Stephen W Scherer

Published in: eLife (2019)

This article has been through an editorial process in which authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (see decision letter).

Keyphrases

induced pluripotent stem cells
endothelial cells
autism spectrum disorder
intellectual disability
spinal cord
pluripotent stem cells
decision making
blood brain barrier